An investigation into the use of orthogonal frequency division multiplexing in packet radio

Bibliography: leaves 56-58.The concept of Orthogonal Frequency Division Multiplexing has been around since the 1960s. It has resurfaced over the last decade as being the modulation scheme of choice in some newer technologies like Digital Video Broadcasting (DVB) and Asynchronous Digital Subscriber lines (ADSL). Amateur packet radio started in 1978 and has attracted thousands of enthusiasts from around the world. The interest in packet radio has waned over the years due advances in the data transmission capabilities oflandline systems and also more widespread access to the Internet. The purpose of this thesis was to develop a simple software simulation model to determine whether or not OFDM could be used to increase the data rates currently available in packet radio systems. The thesis starts out with an introduction to packet radio and OFDM in Chapter 1. A slightly more detailed discussion on OFDM is given in Chapter 2 in order to develop a basic specification for the proposed OFDM model. Chapters 2,3 and 4 discuss the development of the Transmitter model, the Receiver model and the Channel model respectively using the Simulink software package. Chapter 6 discusses the problem of Peak-to-Average Power Ratios (PAPR) in OFDM and explores the use of A-law companding to reduce this problem. In Chapter 7, the developed models are simulated and their performance compared to theoretical expectations. The full system is also simulated in this chapter in order to ascertain the possible data rate through the modelled packet radio channel. Conclusions regarding the application of OFDM to packet radio are presented in Chapter 8

Digital Twin of a Network and Operating Environment Using Augmented Reality

We demonstrate the digital twin of a network, network elements, and operating environment using machine learning. We achieve network card failure localization and remote collaboration over 86 km of fiber using augmented reality

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Physics Design of a High B ouasi-Axisymmetric stellarator

Abstract We have found a new regime of quasi-axisymmetric stellarators which are ballooning stable at high p' Initial studies of the regime are reported. Our results suggest an approach that may be useful more generally for improving the ballooning properties of stellarators

Significant Impacts of Increasing Aridity on the Arid Soil Microbiome

Global deserts occupy one-third of the Earth's surface and contribute significantly to organic carbon storage, a process at risk in dryland ecosystems that are highly vulnerable to climate-driven ecosystem degradation. The forces controlling desert ecosystem degradation rates are poorly understood, particularly with respect to the relevance of the arid-soil microbiome. Here we document correlations between increasing aridity and soil bacterial and archaeal microbiome composition along arid to hyperarid transects traversing the Atacama Desert, Chile. A meta-analysis reveals that Atacama soil microbiomes exhibit a gradient in composition, are distinct from a broad cross-section of nondesert soils, and yet are similar to three deserts from different continents. Community richness and diversity were significantly positively correlated with soil relative humidity (SoilRH). Phylogenetic composition was strongly correlated with SoilRH, temperature, and electrical conductivity. The strongest and most significant correlations between SoilRH and phylum relative abundance were observed for Acidobacteria, Proteobacteria, Planctomycetes, Verrucomicrobia, and Euryarchaeota (Spearman's rank correlation [r(s)] = >0.81; false-discovery rate [q] = <= 0.005), characterized by 10- to 300-fold decreases in the relative abundance of each taxon. In addition, network analysis revealed a deterioration in the density of significant associations between taxa along the arid to hyperarid gradient, a pattern that may compromise the resilience of hyperarid communities because they lack properties associated with communities that are more integrated. In summary, results suggest that arid-soil microbiome stability is sensitive to aridity as demonstrated by decreased community connectivity associated with the transition from the arid class to the hyperarid class and the significant correlations observed between soilRH and both diversity and the relative abundances of key microbial phyla typically dominant in global soils. IMPORTANCE We identify key environmental and geochemical factors that shape the arid soil microbiome along aridity and vegetation gradients spanning over 300 km of the Atacama Desert, Chile. Decreasing average soil relative humidity and increasing temperature explain significant reductions in the diversity and connectivity of these desert soil microbial communities and lead to significant reductions in the abundance of key taxa typically associated with fertile soils. This finding is important because it suggests that predicted climate change-driven increases in aridity may compromise the capacity of the arid-soil microbiome to sustain necessary nutrient cycling and carbon sequestration functions as well as vegetative cover in desert ecosystems, which comprise one-third of the terrestrial biomes on Earth.National Institute of Environmental Health Sciences Superfund Research Program [P42 ES004940]; National Science Foundation Microbial Observatory grant [MCB0604300]; Lewis and Clark Fund for Exploration and Field Research in Astrobiology; Earth Microbiome Project - WM Keck Foundation; John Templeton Foundation; Argonne National LaboratoryOpen Access Journal.This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Factors related to the failure of radiographic recognition of occult posttraumatic pneumothoraces

Purpose: Although posttraumatic pneumothoraces (PTXs) are common and potentially life threatening, the supine chest radiograph (CXR) is an insensitive test for their detection. Computed tomography (CT) often identifies occult pneumothoraces (OPTXs). Previous descriptions of OPTX topography have been poor. Our purpose was to define their distribution and aid in the targeting of thoracic ultrasound. Methods: Posttraumatic supine CXRs and CTs were reviewed for occult, overt, and residual PTXs. PTXs were compared according to their apical, basal, anterior, lateral, medial, and posterior components. A comparative size index was calculated. Results: Among 761 patients, 338 CT scans revealed 103 PTXs in 89 patients; 55% were OPTXs. OPTXs were apical (57%), basal (41%), anterior (84%), lateral (24%), and medial (27%), with 0% posterior. Conclusions: CXR missed over half of all PTXs. OPTXs had a greater anterior versus lateral (nearly 4-fold) and both basal and apical versus lateral (2-fold) distribution. OPTXs are often located at easily accessible sonographic windows.</p